（1.College of Veterinary Medicine，South China Agricultural University，Guangzhou 510642，China；2.Key Laboratory of Biotechnology and Bioproducts Development for Animal Epidemic Prevention of Ministry of Agriculture，P.R.China，Zhaoqing 526238，China；3.Guangdong Provincial Key Laboratory of Biotechnology R & D of Veterinary Biological Products，Zhaoqing 526238，China）
［1］HAQSHENAS G，SHIVAPRASAD H L，WOOLCOCK P R，et al.Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United States ［J］.J Gen Virol，2001，82(10)：2449-2462.
［2］PAYNE C J，ELLIS T M，PLANT S L，et al.Sequence data suggests big liver and spleen disease virus (BLSV) is genetically related to hepatitis E virus ［J］.Vet Microbiol, 1999，68(1-2)：119-125.
［3］HAQSHENAS G，HUANG F F，FENAUX M，et al.The putative capsid protein of the newly identified avian hepatitis E virus shares antigenic epitopes with that of swine and human hepatitis E viruses and chicken big liver and spleen disease virus ［J］.J Gen Virol，2002，83(9)：2201-2209.
［4］BILLAM P，HUANG F F，SUN Z F，et al.Systematic pathogenesis and replication of avian hepatitis E virus in specific-pathogen-free adult chickens ［J］.J Virol，2005，79(6)：3429-3437.
［5］HUANG F F，SUN Z F，EMERSON S U，et al.Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV ［J］.J Gen Virol，2004，85(6)：1609-1618.
［6］HUANG F F，HAQSHENAS G，SHIVAPRASAD H L，et al.Heterogeneity and seroprevalence of a newly identified avian hepatitis e virus from chickens in the United States ［J］.J Clin Microbiol，2002，40(11)：4197-4202.
［7］VITRAL C L，PINTO M A，LEWIS-XIMENEZ L L，et al.Serological evidence of hepatitis E virus infection in different animal species from the Southeast of Brazil ［J］.Mem Inst Oswaldo Cruz，2005，100(2)：117-122.
［8］梁久红，孟继鸿.人、猪、禽戊型肝炎病毒血清学关系的研究［J］.中华微生物学和免疫学杂志，2007，27(7)：581-586.
［9］GUO H，ZHOU E M，SUN Z F，et al.Identification of B-cell epitopes in the capsid protein of avian hepatitis E virus (avian HEV) that are common to human and swine HEVs or unique to avian HEV ［J］.J Gen Virol，2006，87(1)：217-223.
［10］张璐，周恩民，崔治中，等.禽戊型肝炎血清学调查以及与肝脾肿大综合征关系的研究［J］.中国家禽，2008，30(20)：22-24.
［11］ZHAO Q，SUN Y，ZHAO J，et al.Development and application of an indirect ELISA for detection of antibodies against avian hepatitis E virus ［J］.J Virol Methods，2013，187(1)：32-36.
［12］SUN Z F，LARSEN C T，DUNLOP A，et al.Genetic identification of avian hepatitis E virus (HEV) from healthy chicken flocks and characterization of the capsid gene of 14 avian HEV isolates from chickens with hepatitis-splenomegaly syndrome in different geographical regions of the United States［J］.J Gen Virol，2004，85(3)：693-700.
［13］AGUNOS A C，YOO D，YOUSSEF S A，et al.Avian hepatitis E virus in an outbreak of hepatitis-splenomegaly syndrome and fatty liver haemorrhage syndrome in two flaxseed-fed layer flocks in Ontario［J］.Avian Pathol，2006，35(5)：404-412.
［14］BILIC I，JASKULSKA B，BASIC A.Sequence analysis and comparison of avian hepatitis E viruses from Australia and Europe indicate the existence of different genotypes ［J］.J Gen Virol，2009，90(4)：863-873.
［15］MAREK A，BILIC I，PROKOFIEVA I，et al.Phylogenetic analysis of avian hepatitis E virus samples from European and Australian chicken flocks supports the existence of a different genus within the Hepeviridae comprising at least three different genotypes ［J］.Vet Microbiol，2010，145(1-2)：54-61.
［16］ZHAO Q，ZHOU E M，DONG S W，et al.Analysis of avian hepatitis E virus from chickens，China ［J］.Emerg Infect Dis，2010，16(9)：1469-1472.
［17］SUN Z F，LARSEN C T，HUANG F F，et al.Generation and infectivity titration of an infectious stock of avian hepatitis E virus (HEV) in chickens and cross-species infection of turkeys with avian HEV ［J］.J Clin Microbiol，2004，42(6)：2658-2662.
［18］PAYNE C J，PLANT S L，ELLIS T M，et al.The detection of the big liver and spleen agent in infected tissues via intravenous chick embryo inoculation ［J］.Avian Pathol，1993，22(2)：245-256.
［19］GUO H，ZHOU E M，SUN Z F，et al.Protection of chickens against avian hepatitis E virus (avian HEV) infection by immunization with recombinant avian HEV capsid protein ［J］.Vaccine，2007，25(15)：2892-2899.
［20］RIDDELL M A，LI F，ANDERSON D A，et al.Identification of immunodominant and conformational epitopes in the capsid protein of hepatitis E virus by using monoclonal antibodies ［J］.J Virol，2000，74(17)：8011-8017.
［21］DONG S，ZHAO Q，LU M，et al.Analysis of epitopes in the capsid protein of avian hepatitis E virus by using monoclonal antibodies ［J］.J Virol Methods，2011，171(2)：374-380.
LIU Jian, BAI Yilan, LI Xin, GUI Yaping, JU Houbin, GONG Guohua, XIA Luming, CHEN Weifeng, ZHU Xiaoying, CHANG Xiaojing, LI Zengqiang, TANG Congsheng, WANG Jian, ZHAO Hongjin.
VP1 Sequence and Pathogenicity Analysis of Feline Calicivirus Isolates
[J]. Acta Veterinaria et Zootechnica Sinica, 2022, 53(10): 3530-3539.
